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Expression of the orexin receptors is also widely distributed throughout the central nervous system

MetS was induced in a group of 10 animals by feeding them a high-fat diet (HFD) for 24 weeks, while a control group of 10 animals received a normalipid/regular fat diet (ND) (AIN93M) during the same period

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Quantitative endpoints, such as MRI-PDFF and histology, can capture subtle yet clinically meaningful changes, whereas ALT/AST and ultrasonography may miss early metabolic improvements

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DOI: Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-16-0722-6 Online ISBN: 978-981-16-0723-3 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)