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In addition, several studies have confirmed that TXNDC12 also played an important role in cancer development and progression [15, 16], such as TXNDC12 promoted cell growth, migration, and invasion promoting tumorigenicity in human gastric cancer via FAK/ERK signaling pathway [17], TXNDC12 also promoted nuclear translocation of -catenin promoting epithelial-mesenchymal transition process to promote metastasis and invasion of hepatocellular carcinoma [18]

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Fatty liver disease is a condition where fat accumulates in the liver, leading to inflammation and potential damage to the liver cells

Role of free radicals and catalytic metal ions in human disease

Hauck EW, Diemer T, Schmelz HU, Weidner W