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GLP-1 receptor agonists (GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their attributes such as body weight loss, protection of islet cells, promotion of islet cell proliferation and minimal side effects

However, this has not translated into increased cardiovascular risk

2024;385:e078242

Patients diagnosed with diastolic heart failure (HFpEF) account for approximately half of heart failure hospitalizations

Collectively, these effects lead to improved glycemic control in individuals diagnosed with type 2 diabetes

It belongs to a class of medications known as dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists