Common reasons include missing PA documentation, inability to confirm MASH with F2 to F3 fibrosis staging, non-formulary status, or the request being processed under a broad GLP-1/weight loss exclusion instead of a liver indication
For example, if a patient presents with elevated GH and IGF-I, it is important to rule out underlying impairment in renal function as elevated serum GH and IGF-I levels may also be present in patients with CKD, and not diagnose the patient as having acromegaly
But people that maybe moved to the United States to Minnesota or in a place where UVB radiation isn't getting to the atmosphere 12 months out of the year, it's only getting there four months, for example
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For extra punch, Eli Lilly developed a dual agonist called tirzepatide (sold as Zepbound for weight loss), which hits the GLP-1 receptor and a second receptorgastric inhibitory polypeptide (GIP)
However, it's important to consult with a healthcare provider before starting any new supplement, particularly if you have underlying health conditions or are taking other medications
