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Growth hormone levels naturally decline with age, which can contribute to reduced energy levels, decreased muscle mass, impaired cognitive function, and increased risk of chronic diseases

Li, X., Xu, J., Bartolk-Suki, E., Jiang, J

Oxid Med Cell Longev 2022:9678625 Holmes EW, Yong SL, Eiznhamer D, Keshavarzian A (1998) Glutathione content of colonic mucosa: evidence for oxidative damage in active ulcerative colitis

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Enzymatic degradation by proteases and chemical instability can limit therapeutic effectiveness and require specialized storage and handling procedures

Cho SY, Oh Y, Jeong EM,Park SLD, Gong H,Liu X, Zhang G, Na D,Lee J, Chae J