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Activation of Epac2 reduces the concentration of ATP required to achieve closure of K ATP channels promoting membrane depolarisation, Ca 2+ influx and subsequent Ca 2+ -induced Ca 2+ release from intracellular stores, insulin priming and finally insulin granule exocytosis (2931)

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doi: 10.1055/s-0035-1544237, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 61.Misheva M, Kotzamanis K, Davies LC, Tyrrell VJ, Rodrigues PRS, Benavides GA, et al

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