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doi: 10.1111/imr.12541

Key Genetic Factors Driving Cytokine Storm Risk Genetic variants - particularly single nucleotide polymorphisms (SNPs) in promoter regions - can increase baseline or inducible production of pro-inflammatory cytokines

Glutathione degradation takes place in the extracellular space

Indicate that: After 1 half-life, we are at 50% of steady state concentration After 2 half-lives, we are at 75% of steady state concentration After 4 5 half-lives, we are essentially at steady state concentration Next, assume that we stop the infusion