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Hydration: Aim for 2.5 to 3 liters of water daily

Patients experiencing persistent gastrointestinal symptoms that limit protein intake for more than one week should consult their healthcare provider, as dose adjustments or additional supportive interventions may be warranted

Timing patterns from pooled data The STEP trials pooled data reveals several important timing patterns: The incidence of new-onset nausea was highest during the dose escalation period (weeks 1 to 20) and decreased substantially once participants reached maintenance dosing

Common side effects may include: Most side effects are mild and temporary

They fasted before arriving and were given a snack bar to keep caloric intake and stomach contents consistent

In theory, this could shed light on semaglutides effect on vascular co-pathology