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While this is unlikely to interact directly with semaglutide's mechanism, patients with autoimmune conditions or those on immunosuppressive therapy should discuss ashwagandha use with their healthcare team

Although further research is ongoing, research studies show that vitamin B12 deficiency itself can cause pronounced exhaustion and fatigue

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Gradually tapering the dose rather than stopping abruptly helps minimize withdrawal effects

The Trial The ATTAIN-MAINTAIN trial enrolled patients who had achieved substantial weight loss that had plateaued while taking weekly injectable GLP-1s in the SURMOUNT-5 trial

There is limited data on taking semaglutide and phentermine together for weight loss