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Histamine Intolerance & Gluten Connection Histamine intolerance happens when your body cant clear histamine properly due to low DAO enzyme activity, leading to allergy-like symptoms (sneezing, flushing, headaches, gut issues)

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It should be noted that eryptotic RBCs are cleared from the circulation in an efferocytosis-dependent fashion within minutes, in contrast to senescent erythrocytes [77], which require days to be engulfed by macrophages and cleared [72]