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According to a recent study (4), any alterations in glutathione metabolic activity can have a profound effect on cell survival

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This finding agrees with the literature whereby the role of quinone redox metabolism is an ambiguous source of toxicity, with evidence suggesting that redox cycling requires supra-pharmacological concentrations of doxorubicin to generate substantial ROS in tissues and cells 10

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Tokumitsu H, Wayman GA, Muramatsu M, Soderling TR

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The vitamin C transporter SVCT2 (Rohr et al., 2017)

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