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These nuances warrant careful consideration in both clinical practice and public health policymaking
California health officials said Medi-Cal members and their health care providers should consider other treatment options that can support weight loss, such as diet changes, increased activity or exercise, and counseling. That echoes advice from the New Hampshire Medicaid program
Anyone with chronic kidney disease, a history of kidney stones, or reduced kidney function should have their renal function assessed and discuss suitability with their GP or renal specialist before starting, just as they would for the injection
Research has revealed additional benefits beyond those primary uses but some negative side effects have also emerged
Nov 19, 2024, 14:45 ET The trial achieved both its primary endpoints, with semaglutide 2.4 mg demonstrating statistically significant and superior improvements in liver fibrosis with no worsening of steatohepatitis, as well as resolution of steatohepatitis with no worsening of liver fibrosis in people with MASH compared to placebo
However, efpeglenatide was also effective as a biweekly and once-monthly subcutaneous injection, illustrating the opportunity to produce ever longer-acting GLP-1RAs for less frequent administration [39]
