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Combined supplementation with GSH and Se not only attenuated the DEN-induced decrease in serum GPx activity compared with the DEN and DEN + GSH treatments but also yielded similar GPx activity to that observed in control mice (Figure 3E)

doi: 10.1016/j.ejmech.2015.04.040 30 GuoCSunLChenXZhangD

Kawamata, M., Suzuki, H., Kimura, R

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GF mice have decreased 5-HT levels compared to conventional mice, which is rescued following gut microbiota transplantation 287

Third, most trials have short follow-up periods, and long-term efficacy, safety data, and relapse rates in the context of smoking cessation remain lacking