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Abstract To improve the bioavailability and biological activity of recombinant type III humanized collagen (rhCol III), we optimized the preparation process of recombinant type III humanized collagen-loaded liposomes (rhCol III-LIPS) using the film dispersion and periplasmic extrusion methods, with the encapsulation rate as the response value

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Supplementary Materials Data Availability Statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding author.

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Metabolism and Pharmacokinetics (Panel 2) : The drug operates with a rapid 3 to 5 minute half-life, which translates to a short clinical duration of approximately 6 to 10 minutes