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Their jagged mother-son relationship was chronicled for years by Eminem in song, including hits such as "Cleanin' Out My Closet." The internecine hostility also played out in media interviews given by both, becoming one of the trademark traits of Eminem's public profile during the early years of his career

Coherently, the expression of NAD(P)H:quinone oxidoreductase (NQO1) and heme oxygenase-1 (HO-1), two major NF-E2-related factor 2 (Nrf2) regulated anti-oxidant phase II genes 25 , was more abundant in CSE-exposed CCR6 + Th17 cells than in CCR6 neg Th cells (Fig