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M1 microglia release neurotoxic and inflammatory factors such as IL-6, IL-1, and TNF-, contributing to neuronal damage and death, while M2 microglia secrete neurotrophic factors including BDNF, IL-4, and IL-10, fostering neuronal growth and protection (51)

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The Treasury yield curve steepened, with long-term yields rising slightly while short-term rates remained anchored, reflecting shifting expectations around inflation, future Fed policy and increased concerns over fiscal deficits

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"Have I fallen off the wagon

That feeling is real, but it is better described as a nicotine buzz, not a true high