Citation57 CS leads to the production of reactive oxygen species (ROS) which initiate ROS-sensitive signal transduction pathways, such as MAPKs, and various transcription factors, including NF-kB Citation15 resulting in an aberrant cytokine profile
The effects of marijuana on brain development still require further research
Figure 1 3.2 Fluoxetine pretreatment enhances adolescent acquisition of cocaine self-administration via 5-HT 1A receptors To examine the role of endogenous 5-HT in drug reinforcement, we evaluated the effect of fluoxetine pretreatment on subsequent cocaine self-administration in adolescents ( Figure 2 )
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