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While cigarette packaging in Canada no longer displays traditional descriptors like light or mild, differences in nicotine strength still exist between brands and cigarette styles

Effect of Additives on Tobacco Smoke Chemical additives are introduced into cigarette tobacco for a variety of specific purposes, including pH adjustment, maintenance of moisture (humectants), amelioration of the harshness of smoke, control of the burn rate, and impartation of desirable flavor to the smoke (Penn 1997)

Animals were exposed to the smoke for 10 minutes, four times per day, for 10 days

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On the other hand, if a gene is relatively unencumbered, then it might be expressed at higher levels than normal