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It was proposed that acute stimulation of neuronal nicotinic receptors may have beneficial effects on people with AD 8 and that prolonged treatment may have further benefits by increasing neuronal survival 9

They contribute to the release of pro-inflammatory mediators, cell activation, and phagocytosis, and are involved in sensing and amplifying the inflammatory signal

By reducing the amount of time the cigarette continues to burn it is less likely to ignite furniture or bedding material

They activate only when temperatures rise rapidly, usually above 58C, and ignore vapour completely

This approach would align with, and build on, existing requirements in TRPR that restrict certain elements on some vape packaging