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Antidepressant actions via monoamine oxidase inhibition (from unknown components from cigarettes) and nicotine-derived compensation effects of psychiatric medications also rationalize the phenomenon of more smokers among psychiatric patients compared with healthy adults 13

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The 2022 National Drug Survey on Drug Use and Health (NSDUH) reported: 29.5 million people or 10.5% of those aged 12 and older had AUD within the past year

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