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Pots syndrome doesn't develop in the heart but in the autonomic nervous system, which results in a high heart rate and lowering blood pressure

One study found that individuals reported higher tolerance and withdrawal from dabbing, which indicates that dabbing may increase the likelihood of addiction or dependence

The first study investigated the effect of acute exposure to mainstream smoke from a commercial cigarette (Marlboro Red) or aerosol from a heated tobacco product (IQOS) on vascular endothelial function using flow-mediated dilation as an experimental surrogate (Nabavizadeh et al., 2018)