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Adolescents in high-income countries showed no statistically significant differences in the prevalence of tobacco use (p 0.052) (Table 1)

More than three-fourths of adults who currently use tobacco products use combustible products (e.g., cigarettes, cigars, pipes), which are the predominant cause of tobacco-related disease, disability, and death in the United States

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Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach