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Because nicotine affects the development of the brain's reward system, continued nicotine vaping can not only lead to nicotine addiction, but it also can make other drugs such as cocaine and methamphetamine more pleasurable to a teen's developing brain

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Supplementary Information 3: Study quality and bias assessment

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Since the narcotic and psychotropic prescription drugs which are abused in most of South Asia are largely available through pharmacies, there is a need for greater awareness amongst the pharmaceutical trade and industry about the possibility of abuse of these drugs