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By targeting new tobacco products and making them run the gauntlet of the approval process, the FDA would make it exceedingly difficult and costly to introduce new products

Results from the same study showed nonsignificant increase in deaths from lung cancers in heavy smokers compared to light smokers confirming that the significance is lost because the threshold between light and heavy smokers was very low at 3.5 cigarettes per day

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Blood samples were collected 1, 2, 4, 6, 8, 10, 12 and 15 min after the first puff, and nicotine serum levels were measured by liquid chromatography-mass spectrometry (LCMS)

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