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In the data released in the early new year, Health Canada identified that gross sales revenue (exclusive of excise tax and operating costs) on sales of 23.9 billion cigarettes was $4.19 billion (gross revenue of $0.18 per cigarette)

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To be specific, the expression levels of hsa-miR-3913-5p, hsa-miR-574-5p, hsa-miR-500a-5p and piR-50603 in SAE-derived EVs exposed to CSE were significantly upregulated, whereas the expression levels of hsa-miR-618 and pi-R52900 were significantly downregulated [82]

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