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HECT E3 ligases, comprising 28 known members, are subdivided into three categories: NEDD4 family members, HERC family members, and other HECT-type E3 ligases

Physical abuse during adolescence had an even stronger effect this type of mistreatment at that point in life was linked to 3.7 times higher odds for sharply increased cigarette use

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His background of abuse and war horrors qualifies him as a potential tragic hero, but Don is not Oedipus

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Anko even looks and acts like a stereotypical investigator, from her persistent smoking habit to her beige trench coat and her hardboiled dialogue and attitude