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The globally increased BEN is unlikely induced by vascular effects of nicotine

Acknowledgements Financial support for this project was provided by the National Institutes of Health (grant number 1 P01 CA138-389-01), a Canadian Institutes of Health Research New Investigator Award (Hammond), the Canadian Cancer Society Research Institute Junior Investigator Award (Hammond), and the Propel Centre for Population Health Impact

Greater decreases occurred among those with higher income and those with more education

The authors thank all investigators for sharing this data

Army & Navy Panegoric Paregoric referred to a camphorated tincture of opium, famed for centuries for its soothing qualities

How to Avoid It Next Time The goal is to enjoy your buzz, not suffer through it