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Musculoskeletal Corticosteroids decrease bone formation and increase bone resorption both through their effect on calcium regulation (i.e., decreasing absorption and increasing excretion) and inhibition of osteoblast function

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doi:10.1136/tobaccocontrol-2018-054796

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Arnold, 46 at diagnosis, reported no early red flags but progressive unwellness in early 2025: fatigue, lower back pain, and general malaise leading to late-April hospitalization