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In vitro and mouse models of e-cig exposure have found evidence of cell damage and death, increased inflammation, and impaired defenses against both viruses and bacteria (reviewed by (22))

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Albrecht A, Felk A, Pichova I, Naglik JR, Schaller M, de Groot P, Maccallum D, Odds FC, Schfer W, Klis F, Monod M, Hube B: Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions