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Bacterial colonisation is related to greater airway inflammation and frequent acute exacerbations 31,32

In Article 13, it recommends banning not only direct tobacco advertising but also any product that contributes to normalizing tobacco use, including candies or toys that mimic cigarettes (1)

people addicted to opiates replace protein and fats with meals high in sugar and alcohol, which are low in essential nutrients and are empty sources of calories (Mahboub et al., 2020)

So the end mustve been very rapid