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Although these studies suggest that nicotine in e-cig vaping plays a crucial role in compromising stroke outcome, other chemical constituents such as glycerin, propylene glycol, and flavoring agents (Kaur et al., 2018), shown by studies to have specific toxicities, need to be investigated separately for effects on ischemic stroke outcome and potential therapy

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Outcome data were gathered at baseline from September 20, 2001 to February 12, 2002, January 30, 2002 to May 27, 2002 just after the intervention, after a year follow-up from November 28, 2002 to May15, 2003, and after two-year follow-up from November 18, 2003 to May 12, 2004 with questionnaire completed in the classroom