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98 Studies in animal models have shown that nicotine can cause pathological effects similar to those observed with tobacco smoke such as oxidative damage and cerebrovascular impairments that lead to stroke and exacerbate ischemic injury

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Effective methods for managing nicotine withdrawal include: Nicotine Replacement Therapy (NRT) : This involves using products like patches, lozenges, or gum to help reduce cravings and ease withdrawal symptoms

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