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Our findings support a complex polygenetic architecture of ND, with neurobiological indications, including loci shared across smoking traits and ND-specific loci

References Baker RR: Smoke chemistry

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for example, 1.7% of most adults in Great Britain had tried heated tobacco products in 2017

If smoking were eliminated, we predict that these counties would have smoking-related cancer rates that are about the same as the current average rate for all 612 SEER counties (left bar in Fig