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In 1586 the botanist Jaques Dalechamps gave the plant the name of Herba nicotiana , which was also adopted by Linn

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The likelihood of malignant transformation cannot be reliably predicted and is patient specific

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Therefore, it is likely that increased Candida abundance, adhesion and invasion with tobacco usage, and the potential of Candida -induced nitrosative changes plays a role in the development of potentially malignant lesions and progression to cancer [139, 141]