Two cross-sectional studies (122, 131), one of which examined exclusive e-cigarette use (66), found statistically significant worse lung function in daily e-cigarette users than in non-smokers (FVC in one study (122) and in most of the measures [FVC, FEV1, FEV1/FVC ratio, and MFEF 25%75% in the other (131)])
Different cohort results were meta-analyzed using a random effects model
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