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Examination of the association between smoking and frequency of hangover must also consider consumption of alcohol in order to account for differences in both variables that might be attributable to confounds with amount of alcohol consumed, or sex differences in alcohol metabolism or in threshold for inducing hangover (Jackson, 2008)

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Glantz, who also directs the Center for Tobacco Control Research and Education at UCSF, predicted that some tobacco companies "almost certainly" are going to sue claiming that publishing the warnings would prove too onerous

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