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Response biomarkers of inhalation exposure to cigarette smoke in the mouse lung

Absence of PMTA is not automatic disqualification, especially for 0% nicotine products that sit outside that framework

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This equates to approximately 3% of cases, a rate that stands notably higher than the global incidence of lung cancer, and higher compared to 0.83% of lung cancer in Sprague Daley rates not exposed to radon (53, 54)

According to Statistics Canada, about 16.9 per cent of Canadians aged 12 and older (about 5.2 million people) smoked either daily or occasionally in 2016