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In May 1990 Imperial Tobacco, Britains biggest cigarette and cigar maker, announced the closure of the Wills cigar factory, with the loss of all 530 jobs as part of a pre-European Single Market rationalisation designed to make the company the most efficient tobacco manufacturer in Europe. Job losses were also announced at plants in Ipswich and Bristol

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Further details about the challenges were not immediately available

High titer autoantibodies to GM-CSF in patients with AML, CML, and MDS are associated with active disease