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In case that is not feasible, administering 100% oxygen in the preoperative period may significantly expedite the removal of CO as the strong affinity of CO for binding to hemoglobin (250 times more than that of oxygen) can be offset with a decrease in the half-life of CO to 4080 min.[] Limitations of the study include a small sample size since the cost of analysis of both nicotine and CO is high

Tobacco use is harmful to health and causes cancer and other serious diseases.