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A dash (-) indicates no difference between groups

Holts Cigar Company does not sell cigars or tobacco-related products to anyone under the age of 21

The chemical formula for nicotine is CHN, and it works by mimicking the effect of the primary neurotransmitter of the nervous system: acetylcholine (ACh)

1907's "Prince Albert" smoking tobacco became the company's national showcase product, which led to high-profile advertising in New York City's Union Square

Using cigars is associated with increased mortality risk from lung cancer, tobacco-related cancers, and all-causes [4], although the risks may differ based on product sub-type and characteristics (e.g., smoke pH, which affects ease of inhalation) [2]

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