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Large swaths of the Midwest and northeastern United States are currently mired in hazy skies and poor air quality due to migrating smoke from wildfires in Canada and Minnesota

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Pharmacokinetic (PK) studies of conventional cigarette smoking have reported maximum plasma nicotine concentrations (C max ) in the region of 1021 ng/mL, depending on the product used 9,10,11

These data overall indicate that the harmful effects of nicotine should not be underestimated

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