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DOMESTIC DEMAND, CUSTOMER AND BUYER ARCHITECTURE Where Demand Comes From and How It Behaves Consumption / Demand: Historical Data (2012-2025) and Forecast (2026-2035) Demand by End-Use and Buyer Group Demand by Customer / Consumer Segment Purchase Criteria, Switching Logic and Adoption Barriers Replacement, Replenishment and Installed-Base Dynamics Future Demand Outlook 7

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Economy & Productivity Addiction costs countries billions through lost productivity, absenteeism, and healthcare spending

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Youre more likely to have a high level of LDL-C if youre: Hypercholesterolemia is very common