These responses are dose-dependent, correlating with smoking intensity and changes in smoking habits, highlighting the significant role of cigarette smoke in AEP pathogenesis and the importance of smoking cessation for prevention
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3.36.2 Risks associated with low-rate daily smoking A 2018 meta-analysis of 141 cohort studies summarised in 55 scientific papers reported that, on average, smoking only one cigarette per day carries a risk of developing coronary heart disease and stroke much greater than expected: around half that for people who smoke 20 per daythat is, 10/20 th rather than the 1/20 th that might be expected
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The device itself may be sold legally, often branded for use with snuff tobacco
