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Specifically, two APOE-4 alleles carriers were at greatest risk of dementia followed by one-4 allele carriers compared with non-carriers, with an adjusted hazard ratio (HR) of 7.63 (95% confidence interval [CI] 6.469.01) and 2.47 (95% CI 2.222.76), respectively (Table 2)

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Dynamics of smoking-induced genome-wide methylation changes with time since smoking cessation

Well over one billion people use nicotine via its most dangerous delivery system (smoking), and around 8 million people die prematurely each year as a result

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