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Over the counter proton pump inhibitors (PPIs) Omeprazole (Prilosec) Lansoprazole (Prevacid) Esomeprazole (Nexium) Prescription only proton pump inhibitors (PPIs) Pantoprazole (Protonix) Dexlansoprazole (Dexilant) Rabeprazole (Aciphex) Over the counter histamine-2 receptor antagonists (H2Ras) Famotidine (Pepcid) Cimetidine (Tagamet) Medications to treat heartburn may interfere with certain oral chemotherapy agents by raising the pH of the stomach and affecting drug absorption