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Subjects not included in this analysis because they did not have blood samples and lung function measures at three time points were older, had lower lung function, and had higher pack-years of smoking, which would likely bias our results toward the null given that those included were healthier

Completely smoke-free, they provide smokers with a safer alternative to cigarettes while not compromising on the familiar taste of authentic tobacco

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Despite recent announcements, Australia remains the only country to have implemented plain packaging, which is surprising considering that the idea that all tobacco products come in plain brown wrappers was proposed by a group of Canadian doctors in the mid-1980s [7]

& Boulton, A

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