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Vila Petroff MG, Egan JM, Wang X, Sollott SJ: Glucagon- like peptide-1 increases cAMP but fails to augment contraction in adult rat cardiac myocytes

PMID: 19318378

Medications that delay gastric emptying may alter the speed and magnitude of GLP-1 effects

Patients who maintain regular schedules achieve 510% average body weight reduction, while irregular dosing patterns correlate with rebound weight gain and loss of metabolic benefit

This is a theoretical rather than documented concern with Pendulum specifically, but it is worth monitoring INR more frequently during the first month if you take warfarin