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First, the creation of tobacco products, such as cigarettes, produces high volumes of carbon dioxide

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All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases [see Boxed Warning]

This high nicotine concentration offers a powerful alternative for heavy smokers looking to transition to vaping