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Setting efficiency (deff) at 1.5, at 0.05 for a two-sided test with Z 1-/2 equal to 1.96, we calculated the sample size required for this study, which resulted in an estimated minimum sample size of 600 participants per country to be recruited as part of our research efforts

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Smoking may lead to some weight loss by suppressing appetite and increasing metabolism, but it may also lead to changes in how the body distributes fat to certain areas

To truly reduce the damage caused by smoking, e-cigarettes must therefore completely replace cigarettes and not simply serve to reduce the number of cigarettes smoked in a day

Gilks W, Richardson S, Spiegelhalter D (1996) Markov chain Monte Carlo in practice

The interrater agreement among the three reviewers, measured by Fleiss , was 86.1 percent, which is considered to be adequate