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Thing is, along with the liquid, you're losing other components from the leaves, which totally changes the mix

The risk of lung cancer death attributable to smoking for a person 69-73 years old who quit smoking at some time between 55-59 can be compared relative to the risk of lung cancer death attributable to smoking for a person 69-73 years old who continues to smoke, as follows (note that 31 is the annual lung cancer death rate per 100,000 among never smokers 69-73 years old and therefore, is the background rate for that age group)

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alone, with 14% being male smokers and 3% being non-smokers

If you pay close attention to the mechanisms of action for these drugs, you should be able to recognize why nicotine and caffeine have a less intense stimulatory effect